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In this issue we highlight a selection of new Reactive Intermediates for drug discovery chemistry, including recent additions to our unique and expanding collection of N-methyl aminomethyls.
These innovative secondary amines complement our extensive range of minimally-substituted primary aminomethyls and aryl amines-and illustrate our continuing commitment to increasing systematically the diversity space that can be explored during hit generation and hit-to- lead optimization programmes.
Discover the entire Maybridge collection of structurally diverse building blocks on the enclosed CD or structure-search online using new enhanced search tools at www.maybridge.com.
 
CAS
英文名稱
分子式
結(jié)構(gòu)式
N-(1,3-benzodioxol-5-ylmethyl)-N-methylamine
C9 H11 N O2
N-methyl-N-(thieno[2,3-b]pyridin-2-ylmethyl)amine
 
C9 H10 N2 S
N-methyl-N-[(1-methyl-1H-indazol-3-yl)methyl]amine
 
C10 H13 N3
N-[(1,5-Dimethyl-1H-pyrazol-3-yl)methyl]-N-methylamine
C7 H13 N3
N-[4-(1H-imidazol-1-yl)benzyl]-N-methylamine
 
C11 H13 N3
N-methyl-N-[(1-methyl-1H-imidazol-5-yl)methyl]amine
 
C6 H11 N3
N-[(2,5-dimethyl-1,3-oxazol-4-yl)methyl]-N-methylamine
C7 H12 N2 O
N-methyl-N-[(5-phenylisoxazol-3-yl)methyl]amine
 
C11 H12 N2 O
tert-butyl 4-{4-[(methylamino)methyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate
 
C15 H25 N3 O2 S
N-(imidazo[1,2-a]pyridin-6-ylmethyl)-N-methylamine
C9 H11 N3
N-methyl-N-(3-morpholin-4-ylbenzyl)amine
 
C12 H18 N2 O
N-[4-(2-furyl)benzyl]-N-methylamine
C12 H13 N O
N-{[5-(2-furyl)isoxazol-3-yl]methyl}-N-methylamine
C9 H10 N2 O2
N-methyl-N-[3-(morpholin-4-ylmethyl)benzyl]amine
C13 H20 N2 O
N-methyl-N-(4-pyridin-2-ylbenzyl)amine
 
C13 H14 N2
N-methyl-N-(3-pyrimidin-5-ylbenzyl)amine
 
C12 H13 N3
N-methyl-N-(2-pyridin-3-ylbenzyl)amine
 
C13 H14 N2
N-methyl-N-[3-(2-morpholin-4-ylethoxy)benzyl]amine
 
C14 H22 N2 O2
N-methyl-N-{[5-(pyridin-3-yloxy)-2-furyl]methyl}amine
C11 H12 N2 O2
N-methyl-N-[(2-morpholin-4-ylpyridin-4-yl)methyl]amine
 
C11 H17 N3 O
 
N-methyl-N-[(2-pyrrolidin-1-ylpyridin-3-yl)methyl]amine
C11 H17 N3
N-methyl-N-[3-(piperidin-1-ylmethyl)benzyl]amine
C14 H22 N2
N-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]benzyl}amine
 
C14 H23 N3
N-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-ylmethyl)-N-methylamine
 
C8 H11 N O2 S
 
(1-Methyl-1H-indazol-3-yl)methylamine
C9 H11 N3
 
(1,3-dimethyl-1H-pyrazol-5-yl)methylamine
 
C6 H11 N3
2-(1H-pyrazol-1-yl)benzylamine
C10 H11 N3
tert-butyl 4-[4-(aminomethyl)phenyl]tetrahydro-1(2H)-pyrazinecarboxylate
C16 H25 N3 O2
(5-bromo-3-benzo[b]thienyl)methylamine
C9 H8 Br N S
[4-(2-furyl)phenyl]methylamine
C11 H11 N O
 
[3-(morpholinomethyl)phenyl]methylamine
C12 H18 N2 O
[2-(2-morpholinoethoxy)phenyl]methylamine
C13 H20 N2 O2
[3-(2-morpholinoethoxy)phenyl]methylamine
 
C13 H20 N2 O2
(2-morpholinopyrid-4-yl)methylamine
 
C10 H15 N3 O
 
[4-(piperidinomethyl)phenyl]methylamine
 
C13 H20 N2
{4-[(4-methylpiperazin-1-yl)methyl]phenyl}methylamine
C13 H21 N3
4-(2-furyl)aniline
C10 H9 N O
3-pyrrolidin-1-ylaniline
 
C10 H14 N2
3-(morpholin-4-ylmethyl)aniline
C11 H16 N2 O
1-methyl-1H-indol-5-amine
 
C9 H10 N2
2-pyridin-3-ylaniline
C11 H10 N2
3-(piperidin-1-ylmethyl)aniline
C12 H18 N2
3-(1H-1,2,4-triazol-1-ylmethyl)aniline
C9 H10 N4
4-(piperidin-1-ylmethyl)aniline
C12 H18 N2
1,3-benzodioxole-4-carboxylic acid
 
C8 H6 O4
2-(4-Chlorophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
C11 H8 Cl N O2 S
thieno[2,3-b]pyrazine-6-carboxylic acid
C7 H4 N2 O2 S
4-(2-furyl)benzoic acid
C11 H8 O3
benzo[b]furan-3-ylacetic acid
C10 H8 O3
1-methyl-1H-indole-5-carboxylic acid
C10 H9 N O2
2-Pyrid-3-ylbenzoic acid
C12 H9 N O2
 
2,4-diphenyl-1,3-thiazole-5-carboxylic acid
C16 H11 N O2 S
2-morpholinoisonicotinic acid
C10 H12 N2 O3
6-[4-(tert-butoxycarbonyl)piperazin-1-yl]nicotinic acid
C15 H21 N3 O4
4-methyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid
 
C8 H7 N O3
3-(1H-1,2,4-triazol-1-ylmethyl)benzoic acid
 
C10 H9 N3 O2
4-(2-furyl)benzoyl chloride
C11 H7 Cl O2
 
4-(2-methyl-1,3-thiazol-4-yl)benzoyl chloride
 
C11 H8 Cl N O S
benzo[b]furan-3-ylacetyl chloride
C10 H7 Cl O2
857284-13-0
2,4-Diphenyl-1,3-thiazole-5-carbonyl chloride
C16 H10 Cl N O S
 
2-methyl-2H-indazole-3-carbonyl chloride
C9 H7 Cl N2 O
 
1-methyl-5-phenyl-1H-pyrazole-3-carbonyl chloride
 
C11 H9 Cl N2 O
1-methyl-3-phenyl-1H-pyrazole-5-carbonyl chloride
C11 H9 Cl N2 O
5-(2-furyl)-1-methyl-1H-pyrazole-3-carbonyl chloride
C9 H7 Cl N2 O2
2,5-dimethyl-1,3-oxazole-4-carbaldehyde
C6 H7 N O2
2-methyl-6-quinolinecarbaldehyde
C11 H9 N O
5-phenylisoxazole-3-carbaldehyde
 
C10 H7 N O2
tert-butyl 4-(4-formyl-1,3-thiazol-2-yl)tetrahydro-1(2H)-pyridinecarboxylate
C14 H20 N2 O3 S
Thieno[2,3-b]pyrazine-6-carbaldehyde
C7 H4 N2 O S
 
3-(1H-pyrazol-1-yl)benzaldehyde
C10 H8 N2 O
5-bromobenzo[b]thiophene-3-carbaldehyde
 
C9 H5 Br O S
5-(2-furyl)isoxazole-3-carbaldehyde
C8 H5 N O3
1-methyl-1H-indole-5-sulfonyl chloride
C9 H8 Cl N O2 S
2,4-diphenyl-1,3-thiazole-5-sulfonyl chloride
C15 H10 Cl N O2 S2
3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonyl chloride
 
C8 H6 Cl N O4 S
3,5-dimethyl-1-phenyl-1H-pyrazole-4-sulfonyl chloride
 
C11 H11 Cl N2 O2 S
4-(4-isocyanatophenyl)-2-methyl-1,3-thiazole
C11 H8 N2 O S
4-(3-isocyanatobenzyl)morpholine
 
C12 H14 N2 O2
4-isocyanato-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole
 
C11 H5 F3 N2 O S
2-(3-chlorophenyl)-4-isocyanato-1,3-thiazole
C10 H5 Cl N2 O S
2,4-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
 
C11 H18 B N O2 S
1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine
C16 H24 B N O2
2-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-thiazole
 
C16 H20 B N O2 S
tert-butyl 4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]tetrahydro-1(2H)-pyrazinecarboxylate
C20 H32 B N3 O4
1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperidine
C18 H28 B N O2
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2,3-dihydrothieno[3,4-b][1,4]dioxine
C12 H17 B O4 S
 
 


 

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